Hi,
if you have a good working Windows USB Stick (like one created with the Windows 10 Media Creation Tool) then theres nothing to worry when installing Windows 10. The Microsoft Installer is very robust and almost ever brings you to a bootable Windows 10.
One thing i would recommend you is to completely wipe the Disk in the Windows installer before doing the actual installation. Once at the Windows 10 Installer Welcome Screen, press Shift-F10 to get to a command line window. Then run
diskpart
use the command lis dis to show the available disks, then sel dis 1 (or, if you have multiple disks the one you want to wipe), then clean. Now create the Microsoft Structure as follows:
convert gpt
create par efi size=512
create par msr size=100
create par prim
exit
now close the command line window and proceed with the windows installer. Select the large partition during install and everything will be fine.